FUROSEMID 40 mg, comprimate

Nume: FUROSEMID 40 mg, comprimate

Tip: furosemidum

Producator: Labormed SRL

Indicatii: Furosemidul este indicat ?n toate tipurile de edeme grave si ?n cazurile rezistente la tiazide. Este diureticul de electie ?n terapia insuficientei cardiace. Ratiuni similare ?l impun ?n terapia edemului pulmonar acut. De asemenea este indicat ?n edemul cerebral, ?n edeme trombotice locale si edeme gravidice. ?n hipertensiunea arteriala, furosemidul poate fi utilizat singur sau ?n asociatie cu alti agenti antihipertensivi. Este de asemenea indicat ?n insuficienta renala acuta sau cronica severa. ?n intoxicatiile acute medicamentoase se recomanda furosemidul pentru a creste eliminarea toxicului. Este util ?n intoxicatiile cu ioduri, bromuri sau fluoruri. De asemenea poate combate hiperkaliemia.

Contraindicatii: Furosemid 40 mg este contraindicat la pacientii cu stari de hipovolemie sau deshidratare, hipokaliemie, alcaloza, ciroza decompensata ?n stadiul precomatos, insuficienta hepatica avansata, glomerulonefrita acuta, insuficienta renala acuta, hipersensibilitate (?ncrucisata cu sulfamide). Administrarea de Furosemid 40 mg este de asemenea contraindicata ?n intoxicatia cu digitalice.

Precautii: Furosemid 40 mg se administreaza cu prudenta pacientilor cu insuficienta cardiaca grava, diabet, guta, obstructia cailor urinare, hipertrofia prostatei. Pacientii cu diabet trebuie avertizati ca Furosemid 40 mg poate creste nivelul glucozei ?n s?nge, afect?nd testele de glucoza urinara. Pacientii hipertensivi trebuie sa evite medicatiile care duc la cresterea presiunii sanguine. Furosemid 40 mg, ca si alte diuretice, este cuprins ?n lista substantelor dopante (interzise la sportivi).

Reactii: ?n cursul terapiei cu Furosemid 40 mg pot aparea efecte secundare, efecte toxice si/sau efecte alergice. Efectele secundare pot fi dezechilibre hidro-electrolitice, acido-bazice si metabolice. Hipokaliemia este ?n general mai frecventa la ?nceputul tratamentului (c?nd raspunsul diuretic este abundent si restrictia dietetica severa) si ?n cazul tratamentului prelungit. Semnele clinice - slabiciune musculara, parestezii, hiporeflexie, somnolenta, anorexie, greata, constipatie, aritmii ectopice, modificari electrocardiografice caracteristice, mai rar afectarea rinichiului (deficit de concentrare, diminuarea filtrarii glomerulare) - apar c?nd se produce o scadere a potasiului total din organism. Hipokaliemia este ?ndeosebi periculoasa la cirotici, unde poate contribui la declansarea comei hepatice. De asemenea, creste toxicitatea cardiaca a digitalicelor la pacientii digitalizati (risc de aritmii ectopice severe). ?n cursul tratamentului cu Furosemid 40 mg mai pot aparea: hiponatremie cu sau fara alcaloza hipocloremica, hipomagnezinemie (mai frecventa la diabetici si alcoolici), cresterea eliminarii calciului cu negativarea balantei calcice (mai ales la batr?ni), hipocalcemie (numai uneori) cu favorizarea tetaniei.

Compozitie: Un comprimat contine: 40 mg furosemida si excipienti: lactoza, amidon de porumb, dioxid de siliciu coloidal, talc, stearat de magneziu, q.s. pentru un comprimat.

Actiune: Furosemidul, un derivat sulfonamid-benzoic, este un diuretic foarte activ, creste mult eliminarea renala de saruri, este eficace si ?n conditiile unei filtrari glomerulare reduse, reduce presiunea arteriala crescuta si potenteaza medicatia anti-hipertensiva. Efectul diuretic ?ncepe dupa 20-60 minute de la administrarea orala si dureaza 4-6 ore.

Administrare: Furosemid 40 mg se administreaza obisnuit pe cale orala. ?n tratamentul edemelor dozele administrate sunt individualizate de medicul curant ?n conformitate cu raspunsul diuretic al pacientului si ?n sensul obtinerii unui efect terapeutic maxim. De asemenea, este importanta stabilirea dozelor minime necesare mentinerii acestui raspuns. La adulti dozele uzuale sunt de 40-80 mg/zi; ?n caz de ineficacitate se poate creste doza la intervale de 6 ore p?na la obtinerea raspunsului sau cel mult p?na la 240 mg/zi (1-3 prize). ?n insuficienta renala sunt uneori necesare doze mai mari - 500 mg sau 1 g pe zi. ?n general, folosirea de doze mari impune controlul debitului urinar si al electrolitilor si corectarea eventualelor dezechilibre. Faptul ca are o durata scurta de actiune (4-6 ore) obliga la repetarea dozei atunci c?nd se impune o diureza sustinuta. Pentru a evita depletia volumica se recomanda repartizarea dozei totale ?n doua sau mai multe prize, iar pentru a evita nicturia, cele doua doze vor fi administrate una dimineata si una la amiaza. Ori de c?te ori este posibil se revine la administrarea ?n doza unica matinala. ?n hipertensiunea arteriala Furosemid 40 mg se utilizeaza singur sau asociat cu alti agenti antihipertensivi. C?nd este utilizat ca monoterapie se recomanda administrarea a 2 ? 20 mg/zi. Repartizarea dozei zilnice ?n doua prize este necesara pentru a evita reboundul care urmeaza ?n mod obisnuit dupa 6 ore de la pierderea initial crescuta de Na+. Pentru bolnavii hipertensivi care respecta un regim alimentar desodat sau pentru cei tratati si cu alte medicamente antihipertensive sunt suficiente doze mai mici ajustate ?n conformitate cu raspunsul terapeutic. ?n caz de oligurie, (daca filtrarea glomerulara scade sub 20 ml/min) se impun doze mai mari: ?ntre 250-2 000 mg/24 h, din cauza excretiei reduse la nivelul tubului proximal. Argumente similare conduc la doze crescute ?n insuficienta cardiaca severa, refractara. La copii doza orala initiala este de 2 mg/kg corp administrat ?n doza unica. Daca raspunsul diuretic nu este satisfacator doza poate fi crescuta cu 1-2 mg/kg corp, dar nu mai devreme de 6-8 ore de la administrarea precedenta. Nu se recomanda doze mai mari de 6 mg/kg corp. Pentru o terapie de ?ntretinere doza trebuie ajustata la nivelul minim la care se obtine raspunsul eficient.

Vizualizari: 2273

Opiniile pacientilor despre acest medicament

Opinie trimisa de: 123 / 2015-06-01

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